AMG-517

Product Specifications

CAS Number

659730-32-2

Target

TRP Channel

Applications

Neuronal Signaling

Smiles

CC (=O) NC1=NC2=C (C=CC=C2S1) OC3=NC=NC (=C3) C4=CC=C (C=C4) C (F) (F) F

Molecular Formula

C20H13F3N4O2S

Additionnal Information

AMG 517 is a potent and selective TRPV1 antagonist, and antagonizes capsaicin, proton, and heat activation of TRPV1 with IC50 of 0.76 nM, 0.62 nM and 1.3 nM, respectively.

Storage Conditions

2 years -80 in solvent

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