(+) -JQ1
Product Specifications
CAS Number
1268524-70-4
Target
Epigenetic Reader Domain
Applications
Epigenetics
Smiles
CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) OC (C) (C) C) C4=CC=C (C=C4) Cl) C
Molecular Formula
C23H25ClN4O2S
Additionnal Information
(+) -JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4 (1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+) -JQ1 suppresses cell proliferation via inducing autophagy. (+) -JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.
Storage Conditions
2 years -80 in solvent
More Discoveries
Explore Other Products
Browse additional items from our catalog
TL510657V 500 µL Each
Atoh7 Mouse shRNA Lentiviral Particle (Locus ID 53404)
Sign In for Pricing
View Details 
254051 50 µL
Gemin 1 (BCD541, Gemin 1, Gemin-1, Gemin1, OTTHUMP00000125198, OTTHUMP00000223567, OTTHUMP00000223568, OTTHUMP00000224066, OTTHUMP00000226924, SMA 1, SMA 2, SMA 3, SMA 4, SMA, SMA@, SMA1, SMA2, SMA3, SMA4, SMN 1, SMN, SMN-1, SMN1, SMNT, Survival motor neuron Protein, Survival ofmotor neuron 1 (telomeric), survival of motor neuron 1, Survival of motor neuron 1, telomeric, T-BCD541)
Sign In for Pricing
View Details NBP2-71037FR 0.1 mL
Mouse Monoclonal ILK Antibody (OTI2H3) [DyLight 680]
Sign In for Pricing
View Details 
MBS2700005-01 24 Strip Well
Cattle Angiotensin II (AngII) ELISA Kit
Sign In for Pricing
View Details