What is the catalog number for (+) -JQ1?

The catalog number for (+) -JQ1 is C12450-1g.

What sizes are available for (+) -JQ1?

(+) -JQ1 is available in the following size(s): 1 g.

Is (+) -JQ1 in stock?

(+) -JQ1 is currently made to order / not held in immediate stock. Contact us for lead time.

Are there any special shipping requirements for (+) -JQ1?

(+) -JQ1 is requires dry ice shipping.

(+) -JQ1

Product Specifications

CAS Number

1268524-70-4

Target

Epigenetic Reader Domain

Applications

Epigenetics

Smiles

CC1=C (SC2=C1C (=NC (C3=NN=C (N32) C) CC (=O) OC (C) (C) C) C4=CC=C (C=C4) Cl) C

Molecular Formula

C23H25ClN4O2S

Additionnal Information

(+) -JQ1 is a BET bromodomain inhibitor, with IC50 of 77 nM/33 nM for BRD4 (1/2) in cell-free assays, binding to all bromodomains of the BET family, but not to bromodomains outside the BET family. (+) -JQ1 suppresses cell proliferation via inducing autophagy. (+) -JQ1 inhibits the expression of Nuclear receptor binding SET domain protein 3 (NSD3) target genes.