Encorafenib

Product Specifications

CAS Number

1269440-17-6

Synonyms

LGX818

Target

Raf

Applications

MAPK

Smiles

CC (C) N1C=C (C (=N1) C2=C (C (=CC (=C2) Cl) NS (=O) (=O) C) F) C3=NC (=NC=C3) NCC (C) NC (=O) OC

Molecular Formula

C22 H27 Cl F N7 O4 S

Additionnal Information

Encorafenib is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF (V600E) with EC50 of 4 nM. Phase 3.

Storage Conditions

2 years -80 in solvent

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