Encorafenib
Product Specifications
CAS Number
1269440-17-6
Synonyms
LGX818
Target
Raf
Applications
MAPK
Smiles
CC (C) N1C=C (C (=N1) C2=C (C (=CC (=C2) Cl) NS (=O) (=O) C) F) C3=NC (=NC=C3) NCC (C) NC (=O) OC
Molecular Formula
C22 H27 Cl F N7 O4 S
Additionnal Information
Encorafenib is a highly potent RAF inhibitor with selective anti-proliferative and apoptotic activity in cells expressing B-RAF (V600E) with EC50 of 4 nM. Phase 3.
Storage Conditions
2 years -80 in solvent
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