AZD3463
Product Specifications
CAS Number
1356962-20-3
Target
ALK
Applications
Protein Tyrosine Kinase
Smiles
COC1=C (C=CC (=C1) N2CCC (CC2) N) NC3=NC=C (C (=N3) C4=CNC5=CC=CC=C54) Cl
Molecular Formula
C24H25ClN6O
Additionnal Information
AZD3463 is a novel orally bioavailable ALK inhibitor with Ki of 0.75 nM, which also inhibits IGF1R with equivalent potency. AZD3463 suppresses cell viability by inducing both cell apoptosis and autophagy.
Storage Conditions
2 years -80 in solvent
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