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Zotarolimus (ABT-578)

Product Specifications

CAS Number

221877-54-9

Synonyms

A 179578

Target

MTOR

Applications

PI3K/Akt/mTOR

Smiles

CC1CCC2CC (C (=CC=CC=CC (CC (C (=O) C (C (C (=CC (C (=O) CC (OC (=O) C3CCCCN3C (=O) C (=O) C1 (O2) O) C (C) CC4CCC (C (C4) OC) N5C=NN=N5) C) C) O) OC) C) C) C) OC

Molecular Formula

C52H79N5O12

Additionnal Information

Zotarolimus (ABT-578, A 179578) is an analogue of rapamycin, and inhibits FKBP-12 binding with IC50 of 2.8 nM.

Storage Conditions

2 years -80 in solvent

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