GSK923295
Product Specifications
CAS Number
1088965-37-0
Target
Kinesin
Applications
Cytoskeletal Signaling
Smiles
CC (C) OC1=C (C=C (C=C1) C (=O) NC (CC2=CC=C (C=C2) C3=CN4C=CC=C (C4=N3) C (C) O) CNC (=O) CN (C) C) Cl
Molecular Formula
C32H38ClN5O4
Additionnal Information
GSK923295 is a first-in-class, specific allosteric inhibitor of CENP-E kinesin motor ATPase with Ki of 3.2 nM, and less potent to mutant I182 and T183. GSK923295 induces post-mitotic apoptosis. Phase 1.
Storage Conditions
2 years -80 in solvent
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