SM-164
Product Specifications
CAS Number
957135-43-2
Target
IAP
Applications
Apoptosis
Smiles
CC (C (=O) NC1CCCCC2CCC (N2C1=O) C (=O) NC (C3=CC=CC=C3) C4=CN (N=N4) CCCCC5=CC=C (C=C5) CCCCN6C=C (N=N6) C (C7=CC=CC=C7) NC (=O) C8CCC9N8C (=O) C (CCCC9) NC (=O) C (C) NC) NC
Molecular Formula
C62H84N14O6
Additionnal Information
SM-164 is a potent, non-peptide, cell-permeable antagonist of XIAP that targets both the BIR2 and BIR3 domains with IC50 of 1.39 nM. SM-164 induces apoptosis and tumor regression.
Storage Conditions
2 years -80 in solvent
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