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SM-164

Product Specifications

CAS Number

957135-43-2

Target

IAP

Applications

Apoptosis

Smiles

CC (C (=O) NC1CCCCC2CCC (N2C1=O) C (=O) NC (C3=CC=CC=C3) C4=CN (N=N4) CCCCC5=CC=C (C=C5) CCCCN6C=C (N=N6) C (C7=CC=CC=C7) NC (=O) C8CCC9N8C (=O) C (CCCC9) NC (=O) C (C) NC) NC

Molecular Formula

C62H84N14O6

Additionnal Information

SM-164 is a potent, non-peptide, cell-permeable antagonist of XIAP that targets both the BIR2 and BIR3 domains with IC50 of 1.39 nM. SM-164 induces apoptosis and tumor regression.

Storage Conditions

2 years -80 in solvent

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