IWR-1-endo
Product Specifications
CAS Number
1127442-82-3
Synonyms
Endo-IWR 1, IWR-1
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
C1C2C=CC1C3C2C (=O) N (C3=O) C4=CC=C (C=C4) C (=O) NC5=CC=CC6=C5N=CC=C6
Molecular Formula
C25H19N3O3
Additionnal Information
IWR-1-endo (endo-IWR 1, IWR-1) is a Wnt pathway inhibitor with IC50 of 180 nM in L-cells expressing Wnt3A, induces Axin2 protein levels and promotes β-catenin phosphorylation by stabilizing Axin-scaffolded destruction complexes.
Storage Conditions
2 years -80 in solvent
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