IWP-2
Product Specifications
CAS Number
686770-61-6
Target
Wnt/beta-catenin
Applications
Cytoskeletal Signaling
Smiles
CC1=CC2=C (C=C1) N=C (S2) NC (=O) CSC3=NC4=C (C (=O) N3C5=CC=CC=C5) SCC4
Molecular Formula
C22H18N4O2S3
Additionnal Information
IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM in a cell-free assay, selective blockage of Porcn-mediated Wnt palmitoylation, does not affect Wnt/β-catenin in general and displays no effect against Wnt-stimulated cellular responses. IWP-2 specifically inhibits CK1δ.
Storage Conditions
2 years -80 in solvent
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