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MK-8745

Product Specifications

CAS Number

885325-71-3

Target

Aurora Kinase

Applications

Cell Cycle

Smiles

C1CN (CCN1CC2=NC (=CC=C2) NC3=NC=CS3) C (=O) C4=C (C (=CC=C4) Cl) F

Molecular Formula

C20 H19 Cl F N5 O S

Additionnal Information

MK-8745 is a potent and selective Aurora A inhibitor with IC50 of 0.6 nM, more than 450-fold selectivity for Aurora A over Aurora B.

Storage Conditions

2 years -80 in solvent

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