LY2090314
Product Specifications
CAS Number
603288-22-8
Target
GSK-3
Applications
PI3K/Akt/mTOR
Smiles
C1CCN (CC1) C (=O) N2CCN3C=C (C4=CC (=CC (=C43) C2) F) C5=C (C (=O) NC5=O) C6=CN=C7N6C=CC=C7
Molecular Formula
C28H25FN6O3
Additionnal Information
LY2090314 is a potent GSK-3 inhibitor for GSK-3α/β with IC50 of 1.5 nM/0.9 nM; may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 is highly selective towards GSK3 as demonstrated by its fold selectivity relative to a large panel of kinases.
Storage Conditions
2 years -80 in solvent
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