Talazoparib (BMN-673)
Product Specifications
CAS Number
1207456-01-6
Synonyms
LT-673
Target
PARP
Applications
DNA Damage/DNA Repair
Smiles
CN1C (=NC=N1) C2C (NC3=CC (=CC4=C3C2=NNC4=O) F) C5=CC=C (C=C5) F
Molecular Formula
C19H14F2N6O
Additionnal Information
Talazoparib (BMN 673, LT-673) is a novel PARP inhibitor with IC50 of 0.57 nM for PARP1 in a cell-free assay. It is also a potent inhibitor of PARP-2, but does not inhibit PARG and is highly sensitive to PTEN mutation. Phase 3.
Storage Conditions
2 years -80 in solvent
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