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BAY 1000394

Product Specifications

CAS Number

1223498-69-8

Synonyms

Roniciclib

Target

CDK

Applications

Cell Cycle

Molecular Formula

C18H21F3N4O3S

Additionnal Information

BAY 1000394 (Roniciclib) is a potent inhibitor of pan-CDK, that inhibits the kinase activity of the cell-cycle cyclin-dependent kinases (CDKs), with IC50 of 7, 9, 11, 25 and 5 nmol/L for CDK1, CDK2, CDK4, CDK7 and CDK9, respectively. It induces cell-cycle arrest and apoptosis and exhibits potent antitumor activity.

Storage Conditions

2 years -80 in solvent

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