RG-7112

939981-39-2

RO5045337

MDM2/MDMX

Apoptosis

CCOC1=C (C=CC (=C1) C (C) (C) C) C2=NC (C (N2C (=O) N3CCN (CC3) CCCS (=O) (=O) C) (C) C4=CC=C (C=C4) Cl) (C) C5=CC=C (C=C5) Cl

C38H48Cl2N4O4S

RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.

2 years -80 in solvent