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RG-7112

Product Specifications

CAS Number

939981-39-2

Synonyms

RO5045337

Target

MDM2/MDMX

Applications

Apoptosis

Smiles

CCOC1=C (C=CC (=C1) C (C) (C) C) C2=NC (C (N2C (=O) N3CCN (CC3) CCCS (=O) (=O) C) (C) C4=CC=C (C=C4) Cl) (C) C5=CC=C (C=C5) Cl

Molecular Formula

C38H48Cl2N4O4S

Additionnal Information

RG7112 (RO5045337) is an orally bioavailable and selective p53-MDM2 inhibitor with HTRF IC50 of 18 nM.

Storage Conditions

2 years -80 in solvent

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