Duvelisib (IPI-145)
Product Specifications
CAS Number
1201438-56-3
Synonyms
INK1197
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC (C1=CC2=C (C (=CC=C2) Cl) C (=O) N1C3=CC=CC=C3) NC4=NC=NC5=C4NC=N5
Molecular Formula
C22H17ClN6O
Additionnal Information
Duvelisib (IPI-145, INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM in cell-free assays, highly selective for PI3K δ/γ than other protein kinases. Phase 3.
Storage Conditions
2 years -80 in solvent
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