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EPZ005687

Product Specifications

CAS Number

1396772-26-1

Target

Histone Methyltransferase

Applications

Epigenetics

Smiles

CC1=CC (=C (C (=O) N1) CNC (=O) C2=C3C=NN (C3=CC (=C2) C4=CC=C (C=C4) CN5CCOCC5) C6CCCC6) C

Molecular Formula

C32H37N5O3

Additionnal Information

EPZ005687 is a potent and selective inhibitor of EZH2 with Ki of 24 nM in a cell-free assay, 50-fold selectivity against EZH1 and 500-fold selectivity against 15 other protein methyltransferases.

Storage Conditions

2 years -80 in solvent

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