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Bavdegalutamide (ARV-110)

Product Specifications

CAS Number

2222112-77-6

Target

Androgen Receptor

Applications

Endocrinology & Hormones

Smiles

FC1=CC2=C (C=C1N3CCN (CC3) CC4CCN (CC4) C5=NN=C (C=C5) C (=O) NC6CCC (CC6) OC7=CC=C (C#N) C (=C7) Cl) C (=O) N (C8CCC (=O) NC8=O) C2=O

Molecular Formula

C41H43ClFN9O6

Additionnal Information

Bavdegalutamide (ARV-110) is an orally bioavailable, specific androgen receptor (AR) PROTAC degrader that leads to ubiquitination and degradation of AR. ARV-110 completely degrades androgen receptor (AR) in all cell lines tested with DC50 of < 1 nM. ARV-110 can be used for the research of prostate cancer.

Storage Conditions

3 years -20°C powder

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