MD-224
Product Specifications
CAS Number
2136247-12-4
Target
MDM2/MDMX
Applications
Apoptosis
Molecular Formula
C48H43Cl2FN6O6
Additionnal Information
MD-224 is a highly potent and effective degrader of the Human murine double minute 2 (MDM2) protein, the main cellular inhibitor of the tumor suppressor p53. It strongly inhibits cell growth in leukemia cell lines with wild-type p53 and induces complete and lasting tumor regression in the RS4;11 xenograft tumor model.
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