HI-TOPK-032
Product Specifications
CAS Number
487020-03-1
Target
TOPK
Applications
MAPK
Smiles
C1=CC=C2C (=C1) N=C3C (=C4C=C (C=CN4C3=N2) NC (=O) C5=CC=CS5) C#N
Molecular Formula
C20H11N5OS
Additionnal Information
HI-TOPK-032 is a potent and specific inhibitor of TOPK. HI-TOPK-032 also reduces ERK-RSK phosphorylation, regulates of the abundance of p53, cleaved caspase-7, and cleaved PARP, and induces apoptosis in cancer cells.
Storage Conditions
3 years -20°C powder
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