Alflutinib (Furmonertinib) mesylate
Product Specifications
CAS Number
2130958-55-1
Synonyms
AST2818 mesylate
Target
EGFR
Applications
Protein Tyrosine Kinase
Smiles
CN1C=C (C2=CC=CC=C21) C3=NC (=NC=C3) NC4=C (N=C (C (=C4) NC (=O) C=C) N (C) CCN (C) C) OCC (F) (F) F
Molecular Formula
C29H35F3N8O5S
Additionnal Information
Alflutinib (Furmonertinib) mesylate is a third-generation epidermal growth factor receptor (EGFR) inhibitor that inhibits both EGFR-sensitive mutations and T790M mutations. Alflutinib (AST2818), primarily metabolized by CYP3A4, is also a potent CYP3A4 inducer with EC50 of 0.25 μM.
Storage Conditions
3 years -20°C powder
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