Valinomycin

Product Specifications

CAS Number

2001-95-8

Synonyms

NSC 122023

Smiles

CC ([C@@H] (O1) C (N[C@] (C (O[C@H] (C (N[C@H] (C (O[C@@H] (C (N[C@@H] (C (O[C@] (C) ([H]) C (N[C@@H] (C (C) C) C (O[C@H] (C (C) C) C (N[C@H] (C (C) C) C (O[C@@H] (C) C (N[C@] (C (C) C) ([H]) C1=O) =O) =O) =O) =O) =O) =O) C (C) C) =O) C (C) C) =O) C (C) C) =O) C) =O) ([H]) C (C) C) =O) C

Molecular Formula

C54H90N6O18

Additionnal Information

Valinomycin (NSC 122023) is a potassium-specific ionophore that selectively complexes with K+ ions and integrates into biological bilayer membranes via its hydrophobic exterior, disrupting the normal K+ gradient. This disruption leads to membrane depolarization and subsequent cell death, while encapsulation in liposomes can reduce its cytotoxicity and improve targeting precision.