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RA-190

Product Specifications

CAS Number

1617495-03-0

Target

Proteasome

Applications

Proteases

Smiles

C1C (=CC2=CC (=C (C=C2) Cl) Cl) C (=O) C (=CC3=CC (=C (C=C3) Cl) Cl) CN1C (=O) C (CC4=CC=CC=C4) N.Cl

Molecular Formula

C28H23Cl5N2O2

Additionnal Information

RA190, a bis-benzylidine piperidon, is a potent, selective and oral effective inhibitor of proteasome ubiquitin receptor RPN13/ADRM1 with anticancer activity. RA190 triggers ER stress response, p53/p21 signaling axis and autophagy in multiple myeloma cells.

Storage Conditions

3 years -20°C powder

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