RA-190
Product Specifications
CAS Number
1617495-03-0
Target
Proteasome
Applications
Proteases
Smiles
C1C (=CC2=CC (=C (C=C2) Cl) Cl) C (=O) C (=CC3=CC (=C (C=C3) Cl) Cl) CN1C (=O) C (CC4=CC=CC=C4) N.Cl
Molecular Formula
C28H23Cl5N2O2
Additionnal Information
RA190, a bis-benzylidine piperidon, is a potent, selective and oral effective inhibitor of proteasome ubiquitin receptor RPN13/ADRM1 with anticancer activity. RA190 triggers ER stress response, p53/p21 signaling axis and autophagy in multiple myeloma cells.
Storage Conditions
3 years -20°C powder
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