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DIM-C-pPhOH

Product Specifications

CAS Number

151358-47-3

Synonyms

C-DIM8, CDIM8

Target

Nur77

Applications

Apoptosis

Smiles

C1=CC=C2C (=C1) C (=CN2) C (C3=CC=C (C=C3) O) C4=CNC5=CC=CC=C54

Molecular Formula

C23H18N2O

Additionnal Information

DIM-C-pPhOH (C-DIM8, CDIM8) is a nuclear receptor 4A1 (NR4A1) (Nur77) antagonist. DIM-C-pPhOH inhibits tumor growth and mTOR signaling, induces apoptosis and cellular stress. DIM-C-pPhOH reduces cell proliferation with IC50 of 13.6 μM and 13.0 μM for ACHN cells and 786-O cells, respectively.

Storage Conditions

3 years -20°C powder

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