VU0357017 Hydrochloride
Product Specifications
CAS Number
1135242-13-5
Synonyms
CID-25010775
Target
AChR
Applications
Neuronal Signaling
Smiles
CCOC (=O) N1CCC (CC1) NCCNC (=O) C2=CC=CC=C2C.Cl
Molecular Formula
C18H28ClN3O3
Additionnal Information
VU0357017 hydrochloride (CID-25010775) is a potent, highly selective and CNS-penetrant agonist of M1 which is a subtype of muscarinic acetylcholine receptors (mAChRs) . VU0357017 hydrochloride appears to act at an allosteric site to activate the receptor with EC50 of 477 nM and Ki of 9.91 μM.
Storage Conditions
3 years -20°C powder
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