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VU0357017 Hydrochloride

Product Specifications

CAS Number

1135242-13-5

Synonyms

CID-25010775

Target

AChR

Applications

Neuronal Signaling

Smiles

CCOC (=O) N1CCC (CC1) NCCNC (=O) C2=CC=CC=C2C.Cl

Molecular Formula

C18H28ClN3O3

Additionnal Information

VU0357017 hydrochloride (CID-25010775) is a potent, highly selective and CNS-penetrant agonist of M1 which is a subtype of muscarinic acetylcholine receptors (mAChRs) . VU0357017 hydrochloride appears to act at an allosteric site to activate the receptor with EC50 of 477 nM and Ki of 9.91 μM.

Storage Conditions

3 years -20°C powder

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