Thalidomide-O-COOH (Cereblon ligand 3)
Product Specifications
CAS Number
1061605-21-7
Synonyms
E3 ligase Ligand 3
Target
E3 Ligase
Applications
Ubiquitin
Smiles
C1CC (=O) NC (=O) C1N2C (=O) C3=C (C2=O) C (=CC=C3) OCC (=O) O
Molecular Formula
C15H12N2O7
Additionnal Information
Thalidomide-O-COOH (Cereblon ligand 3, E3 ligase Ligand 3), a Thalidomide-based Cereblon (CRBN) ligand, is used in the recruitment of CRBN protein. Thalidomide-O-COOH (Cereblon ligand 3) can be connected to the ligand for protein by a linker to form PROTACs (Proteolysis Targeting Chimera) .
Storage Conditions
3 years -20°C powder
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