Ellipticine hydrochloride
Product Specifications
CAS Number
5081-48-1
Synonyms
NSC 71795 hydrochloride, PZE
Target
P450 (e.g. CYP17)
Applications
Metabolism
Smiles
CC1=C2C=CN=CC2=C (C3=C1NC4=CC=CC=C43) C.Cl
Molecular Formula
C17H15ClN2
Additionnal Information
Ellipticine Hydrochloride (NSC 71795, PZE) is a potent inhibitor of DNA topoisomerase II and forms covalent DNA adducts mediated by its oxidation with cytochromes P450 (CYP) and peroxidases. Ellipticine Hydrochloride is a natural product isolated from the Australian evergreen tree of the Apocynaceae family with antineoplastic activity.
Storage Conditions
3 years -20°C powder
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