DM1 (Mertansine)
Product Specifications
CAS Number
139504-50-0
Synonyms
Maytansinoid DM1
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Smiles
COC1\C=C\C=C (C) \CC2=CC (=C (Cl) C (=C2) OC) N (C) C (=O) CC (OC (=O) C (C) N (C) C (=O) CCS) C3 (C) OC3C (C) C4CC1 (O) NC (=O) O4
Molecular Formula
C35H48ClN3O10S
Additionnal Information
DM1 (Mertansine), an antibody-conjugatable maytansinoid, is a selective microtubule inhibitor that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. Mertansine can be attached to a monoclonal antibody with a linker to create an antibody-drug conjugate (ADC) .Solutions are unstable and should be fresh-prepared.
Storage Conditions
3 years -20°C powder
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