VERU-111
Product Specifications
CAS Number
1332881-26-1
Synonyms
APP-111, Bisindole, ABI-231
Target
Microtubule Associated
Applications
Cytoskeletal Signaling
Molecular Formula
C21H19N3O4
Additionnal Information
Sabizabulin (VERU-111, ABI-231) is a potent, orally bioavailable inhibitor of tubulin that binds to the colchicine binding site. It inhibits the expression of β tubulin (III, IV) and α tubulin, with the potential to treat prostate cancer. It also exhibits significant anti-proliferative activity, with an average IC50 of 5.2 nM across a broad panel of cancer cell lines.
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