Bozitinib

Product Specifications

CAS Number

1440964-89-5

Synonyms

PLB-1001, CBT-101, APL-101, CBI-3103

Target

C-Met

Applications

Protein Tyrosine Kinase

Smiles

CN1C=C2C=C (C (=CC2=N1) F) C (C3=NN=C4N3N=C (C=C4) C5=CN (N=C5) C6CC6) (F) F

Molecular Formula

C20H15F3N8

Additionnal Information

Bozitinib is a highly selective ATP-competitive c-Met inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) selectively inhibits MET-altered tumor cells in preclinical models.

Storage Conditions

3 years -20°C powder

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