What is the catalog number for JG98?

The catalog number for JG98 is C12151-25mg.

What sizes are available for JG98?

JG98 is available in the following size(s): 25 mg.

JG98 is currently made to order / not held in immediate stock. Contact us for lead time.

JG98

Product Specifications

CAS Number

1456551-16-8

Target

HSP (HSP90)

Applications

Cytoskeletal Signaling

Smiles

CCN1C (=CC2=[N+] (C=CS2) CC3=CC=CC=C3) SC (=C4N (C5=C (S4) C=C (C=C5) Cl) C) C1=O.[Cl-]

Molecular Formula

C24H21Cl2N3OS3

Additionnal Information

JG-98 is an allosteric inhibitor of Hsp70 that binds tightly to a deep pocket that is conserved in members of the Hsp70 family. JG-98 induces classical apoptosis features, including morphological changes consistent with programmed cell death and positive annexin staining. JG-98 exhibits anticancer activity.