What is the catalog number for ITD-1?

The catalog number for ITD-1 is C12144-10mM/1mL.

What sizes are available for ITD-1?

ITD-1 is available in the following size(s): 10 mM/1mL.

ITD-1 is currently made to order / not held in immediate stock. Contact us for lead time.

ITD-1

Product Specifications

CAS Number

1099644-42-4

Target

TGF-beta/Smad

Applications

TGF-beta/Smad

Smiles

CCOC (=O) C1=C (NC2=C (C1C3=CC=C (C=C3) C4=CC=CC=C4) C (=O) CC (C2) (C) C) C

Molecular Formula

C27H29NO3

Additionnal Information

ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I (TGFBR1) or type II (TGFBR2) TGFβ receptors but potently blocks phosphorylation of the effector SMAD2/3 proteins induced by TGFβ2, and only minimally in response to Activin A.