ITD-1
Product Specifications
CAS Number
1099644-42-4
Target
TGF-beta/Smad
Applications
TGF-beta/Smad
Smiles
CCOC (=O) C1=C (NC2=C (C1C3=CC=C (C=C3) C4=CC=CC=C4) C (=O) CC (C2) (C) C) C
Molecular Formula
C27H29NO3
Additionnal Information
ITD-1 is a potent TGF-β inhibitor. It does not block the kinase activity of either type I (TGFBR1) or type II (TGFBR2) TGFβ receptors but potently blocks phosphorylation of the effector SMAD2/3 proteins induced by TGFβ2, and only minimally in response to Activin A.
Storage Conditions
3 years -20°C powder
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