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(R) -GNE-140

Product Specifications

CAS Number

2003234-63-5

Target

Dehydrogenase

Applications

Metabolism

Smiles

C1COCCN1C2=CC=C (C=C2) C3 (CC (=C (C (=O) N3) SC4=CC=CC=C4Cl) O) C5=CSC=C5

Molecular Formula

C25H23ClN2O3S2

Additionnal Information

(R) -GNE-140 is an inhibitory agent for LDHA, LDHB, and LDHC, with IC50 values ​​of 3 nM and 5 nM for LDHA and LDHB, respectively. (R) -GNE-140 is 18 times more potent than its S isomer.

Storage Conditions

3 years -20°C powder

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