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VcMMAE

Product Specifications

CAS Number

646502-53-6

Synonyms

Mc-vc-PAB-MMAE

Target

Microtubule Associated

Applications

Cytoskeletal Signaling

Smiles

CCC (C) C (C (CC (=O) N1CCCC1C (C (C) C (=O) NC (C) C (C2=CC=CC=C2) O) OC) OC) N (C) C (=O) C (C (C) C) NC (=O) C (C (C) C) N (C) C (=O) OCC3=CC=C (C=C3) NC (=O) C (CCCNC (=O) N) NC (=O) C (C (C) C) NC (=O) CCCCCN4C (=O) C=CC4=O

Molecular Formula

C68H105N11O15

Additionnal Information

VcMMAE (mc-vc-PAB-MMAE), a MMAE derivative with valine-citrulline (Vc) linker, is an Drug-linker Conjugate for antibody-drug conjugate (ADC) with potent antitumor activity. MMAE is a synthetic antineoplastic agent and can be efficiently released from VcMMAE in vitro and exert cytotoxic activity.

Storage Conditions

3 years -20°C powder

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