Seladelpar
Product Specifications
CAS Number
851528-79-5
Synonyms
MBX-8025
Target
PPAR
Applications
DNA Damage/DNA Repair
Molecular Formula
C21H23F3O5S
Additionnal Information
Seladelpar (MBX-8025) is a potent and selective agonist of peroxisome proliferator–activated receptor-delta (PPAR-δ) with EC50 of 2 nM for human PPAR-δ. MBX-8025 enhances insulin sensitivity, counters dyslipidemia, and reduces hepatic storage of lipotoxic lipids, thereby ameliorating NASH pathology in obese diabetic mice.
Storage Conditions
2 years -20°C liquid
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