GNE-493
Product Specifications
CAS Number
1033735-94-2
Target
PI3K
Applications
PI3K/Akt/mTOR
Smiles
CC (C) (C1=CC2=C (S1) C (=NC (=N2) C3=CN=C (N=C3) N) N4CCOCC4) O
Molecular Formula
C17H20N6O2S
Additionnal Information
GNE-493 (compound 5) is a potent, selective and orally available dual inhibitor of pan-PI3-kinase and mTOR with IC50 of 3.4 nM, 12 nM, 16 nM, 16 nM and 32 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ and mTOR, respectively.
Storage Conditions
3 years -20°C powder
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