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AG 494

Product Specifications

CAS Number

133550-35-3

Target

EGFR

Applications

Protein Tyrosine Kinase

Smiles

C1=CC=C (C=C1) NC (=O) C (=CC2=CC (=C (C=C2) O) O) C#N

Molecular Formula

C16H12N2O3

Additionnal Information

AG-494, a member of the tyrphostin family of tyrosine kinase inhibitors, is a potent inhibitor of EGF receptor autophosphorylation (IC50=1.2 μM) and EGF-dependent cell growth (IC50=6 μM) .

Storage Conditions

3 years -20°C powder

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