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SD 0006

Product Specifications

CAS Number

271576-80-8

Target

P38 MAPK

Applications

MAPK

Smiles

C1CN (CCC1C2=C (C (=NN2) C3=CC=C (C=C3) Cl) C4=NC=NC=C4) C (=O) CO

Molecular Formula

C20H20ClN5O2

Additionnal Information

SD0006 is an inhibitor of p38 kinase-alpha (p38alpha) with IC50 values of 0.016 μM and 0.677 μM for p38α and p38β. It is selective for p38α kinase over 50 other kinases screened (including p38γ and p38δ with modest selectivity over p38β) .

Storage Conditions

3 years -20°C powder

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