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CCCP

Product Specifications

CAS Number

555-60-2

Synonyms

Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone

Target

STING

Applications

Immunology & Inflammation

Smiles

C1=CC (=CC (=C1) Cl) NN=C (C#N) C#N

Molecular Formula

C9H5ClN4

Additionnal Information

CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone), an oxidative phosphorylation inhibitor, is a protonophore mitochondrial uncoupler that increases membrane permeability to protons, leading to a disruption in the mitochondrial membrane potential. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), the protonophore, can inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP) .

Storage Conditions

3 years -20°C powder

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