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Prexasertib (LY2606368)

Product Specifications

CAS Number

1234015-52-1

Synonyms

ACR 368

Target

Chk

Applications

Cell Cycle

Smiles

COC1=C (C2=CC (=N[NH]2) NC3=CN=C (C=N3) C#N) C (=CC=C1) OCCCN

Molecular Formula

C18H19N7O2

Additionnal Information

Prexasertib (LY2606368, ACR 368) is a selective ATP competitor inhibitor of Chk1 and Chk2 with IC50s of 1 nM and 8 nM in cell-free assays, respectively. Prexasertib also inhibits RSK1 with an IC50 of 9 nM in cell-free assay.

Storage Conditions

3 years -20°C powder

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