PMX-53
Product Specifications
CAS Number
219639-75-5
Target
Immunology & Inflammation related
Applications
Immunology & Inflammation
Smiles
CC (=O) NC (CC1=CC=CC=C1) C (=O) NC2CCCNC (=O) C (CCCN=C (N) N) NC (=O) C (CC3=C[NH]C4=CC=CC=C34) NC (=O) C (CC5CCCCC5) NC (=O) C6CCCN6C2=O
Molecular Formula
C47H65N11O7
Additionnal Information
PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. PMX-53 is also an agonist of Mas-related gene 2 (MrgX2) .
Storage Conditions
3 years -20°C powder
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