H-1152 dihydrochloride
Product Specifications
CAS Number
871543-07-6
Synonyms
H-1152 2HCl
Target
Aurora Kinase
Applications
Cell Cycle
Smiles
Cl.Cl.CC1CNCCCN1[S] (=O) (=O) C2=CC=CC3=C2C (=CN=C3) C
Molecular Formula
C16H23Cl2N3O2S
Additionnal Information
H-1152 dihydrochloride (2HCl) is a membrane-permeable and selective inhibitor of Rho-associated protein kinase (ROCK) . H-1152 inhibits ROCK2, PKA, PKC, PKG, AuroraA and CaMK2 with IC50 of 0.0120 μM, 3.03 μM, 5.68 μM, 0.360 μM, 0.745 μM and 0.180 μM, respectively.
Storage Conditions
3 years -20°C powder
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