ICCB-19 hydrochloride
Product Specifications
CAS Number
1803605-68-6
Target
RIP kinase
Applications
Apoptosis
Smiles
Cl.O=C (CSC1=NCCN1) NC2CCCCCC2
Molecular Formula
C12H22ClN3OS
Additionnal Information
ICCB-19 hydrochloride is an inhibitor of TNFRSF1A Associated Via Death Domain (TRADD) with IC50 of 1.12 μM and 2.01 μM for protecting Velcade-induced apoptosis in Jurkat cells and protecting RDA in MEFs, respectively. ICCB-19 indirectly inhibits Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) . ICCB-19 effectively induces autophagy.
Storage Conditions
3 years -20°C powder
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS9355193 Inquire
Pigeon LON Peptidase N-Terminal Domain and RING Finger Protein 2 (LONRF2) ELISA Kit
Sign In for Pricing
View Details CXB28241-01 100 mg
2-Amino-2- (3-chloro-4-fluorophenyl) ethan-1-ol hydrochloride
Sign In for Pricing
View Details CXB28241-02 1 g
2-Amino-2- (3-chloro-4-fluorophenyl) ethan-1-ol hydrochloride
Sign In for Pricing
View Details abx269271 100 µg
Squamous Cell Carcinoma Antigen Recognized By T-Cells 3 (SART3) Peptide
Sign In for Pricing
View Details