Dabigatran etexilate mesylate
Product Specifications
CAS Number
872728-81-9
Synonyms
Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate
Target
Thrombin
Applications
Proteases
Smiles
CCCCCCOC (=O) NC (=N) C1=CC=C (NCC2=NC3=C (C=CC (=C3) C (=O) N (CCC (=O) OCC) C4=CC=CC=N4) [N]2C) C=C1.C[S] (O) (=O) =O
Molecular Formula
C35H45N7O8S
Additionnal Information
Dabigatran etexilate mesylate (Pradaxa, BIBR 1048MS, Dabigatran etexilate methanesulfonate) is an orally active prodrug of Dabigatran which is a reversible and selective, direct thrombin inhibitor (DTI) . Dabigatran selectively and reversibly inhibits human thrombin with Ki of 4.5 nM and thrombin-induced platelet aggregation with IC50 of 10 nM.
Storage Conditions
3 years -20°C powder
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